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Index > Protein center > Umod(Gene name) > Mouse
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  • Umod (Gene name),
  • Uromodulin (Protein name ),  UROM_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Umod;
    Protein name:
    Uromodulin;
    Alternative:
    Tamm-Horsfall urinary glycoprotein(THP);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Uromodulin, secreted form: Secreted into urine after proteolytically cleaveage. Into the urine, may contribute to colloid osmotic pressure, retards passage of positively charged electrolytes, prevents urinary tract infection and modulates formation of supersaturated salts and their crystals.
    Subcellular Location:
    Uromodulin, secreted form Secreted
    Protein Attributes:
    Sequence length:
    642
    Sequence:
    50:
    MGIPLTWMLL | VMMVTSWFTL | AEASNSTEAR | RCSECHNNAT | CTVDGVVTTC | 
    100:
    SCQTGFTGDG | LVCEDMDECA | TPWTHNCSNS | SCVNTPGSFK | CSCQDGFRLT | 
    150:
    PELSCTDVDE | CSEQGLSNCH | ALATCVNTEG | DYLCVCPEGF | TGDGWYCECS | 
    200:
    PGSCEPGLDC | LPQGPDGKLV | CQDPCNTYET | LTEYWRSTEY | GVGYSCDAGL | 
    250:
    HGWYRFTGQG | GVRMAETCVP | VLRCNTAAPM | WLNGSHPSSS | EGIVSRTACA | 
    300:
    HWSDQCCRWS | TEIQVKACPG | GFYIYNLTAP | PECNLAYCTD | PSSVEGTCEE | 
    350:
    CRVDEDCISD | NGRWRCQCKQ | DSNITDVSQL | EYRLECGAND | IKMSLRKCQL | 
    400:
    QSLGFMNVFM | YLNDRQCSGF | SESDERDWMS | IVTPARNGPC | GTVLRRNETH | 
    450:
    ATYSNTLYLA | NAIIIRDIII | RMNFECSYPL | DMKVSLKTSL | QPMVSALNIS | 
    500:
    LGGTGKFTVR | MALFQSPTYT | QPHQGPSVML | STEAFLYVGT | MLDGGDLSRF | 
    550:
    VLLMTNCYAT | PSSNSTDPVK | YFIIQDSCPR | TEDTTIQVTE | NGESSQARFS | 
    600:
    VQMFRFAGNY | DLVYLHCEVY | LCDSTSEQCK | PTCSGTRFRS | GNFIDQTRVL | 
    642:
    NLGPITRQGV | QASVSKAASS | NLRLLSIWLL | LFPSATLIFM | VQ
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    Pfam:
    UniGene:
    Pfam:
    String:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Uromodulin
    Cat.:
    E2280m
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    Packing:
    96T
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    ELISA Kit for Mouse Uromodulin
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    E2280h
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    MSDS:
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    96T
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    ELISA Kit for Mouse Uromodulin
    Cat.:
    E2280r
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    MSDS:
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    96T
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    ELISA Kit for Mouse Uromodulin
    Cat.:
    E2280d
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    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse Uromodulin
    Cat.:
    E2280b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse Uromodulin
    Cat.:
    U2280b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Uromodulin
    Cat.:
    U2280m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Uromodulin
    Cat.:
    U2280h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Uromodulin
    Cat.:
    U2280r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Uromodulin
    Cat.:
    U2280d
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Mouse Uromodulin
    Polyclonal Antibody for Mouse Uromodulin
    Cat.:
    P2280Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Uromodulin
    Cat.:
    P2280Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Uromodulin
    Cat.:
    P2280Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Uromodulin
    Monoclonal Antibody for Mouse Uromodulin
    Monoclonal Antibody for Mouse Uromodulin
    Monoclonal Antibody for Mouse Uromodulin
    Monoclonal Antibody for Mouse Uromodulin
    Monoclonal Antibody for Mouse Uromodulin
    Protein for Mouse Uromodulin
    Protein for Mouse Uromodulin
    Protein for Mouse Uromodulin
    Protein for Mouse Uromodulin
    Protein for Mouse Uromodulin

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    References
    1. 1.
      "Nucleotide sequence and peptide motifs of mouse uromodulin (Tamm-Horsfall protein) -- the most abundant protein in mammalian urine."
      Prasadan K. , Bates J. , Badgett A. , Dell M. , Sukhatme V. , Yu H. , Kumar S.
      Biochim. Biophys. Acta1260:328-332(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Kidney.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: FVB/N.
      tissue: Liver.
    4. 4.
      "The ZP domain is a conserved module for polymerization of extracellular proteins."
      Jovine L. , Qi H. , Williams Z. , Litscher E. , Wassarman P.M.
      Nat. Cell Biol.4:457-461(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION;DOMAIN ZP
    5. 5.
      "Tamm-Horsfall protein knockout mice are more prone to urinary tract infection: rapid communication."
      Bates J.M. , Raffi H.M. , Prasadan K. , Mascarenhas R. , Laszik Z. , Maeda N. , Hultgren S.J. , Kumar S.
      Kidney Int.65:791-797(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE;FUNCTION
    6. 6.
      "Tamm-Horsfall protein is a critical renal defense factor protecting against calcium oxalate crystal formation."
      Mo L. , Huang H.Y. , Zhu X.H. , Shapiro E. , Hasty D.L. , Wu X.R.
      Kidney Int.66:1159-1166(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE;FUNCTION
    7. 7.
      "Urinary uromodulin carries an intact ZP domain generated by a conserved C-terminal proteolytic cleavage."
      Santambrogio S. , Cattaneo A. , Bernascone I. , Schwend T. , Jovine L. , Bachi A. , Rampoldi L.
      Biochem. Biophys. Res. Commun.370:410-413(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 573-587;PROTEOLYTIC CLEAVAGE;IDENTIFICATION BY MASS SPECTROMETRY
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